Intracranial Dysgerminomas
نویسندگان
چکیده
منابع مشابه
Prevalence of c-KIT Mutations in Gonadoblastoma and Dysgerminomas of Patients with Disorders of Sex Development (DSD) and Ovarian Dysgerminomas
Activating c-KIT mutations (exons 11 and 17) are found in 10-40% of testicular seminomas, the majority being missense point mutations (codon 816). Malignant ovarian dysgerminomas represent ~3% of all ovarian cancers in Western countries, resembling testicular seminomas, regarding chromosomal aberrations and c-KIT mutations. DSD patients with specific Y-sequences have an increased risk for Type ...
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A monoclonal antibody (M2A, IgG2a) was produced against a cultured human ovarian epithelial adenocarcinoma cell line, HEY. Monoclonal antibody M2A reacted with a glycoprotein of molecular weight 40,000 on the surface of HEY cells. The affinity constant of the monoclonal antibody M2A for HEY cells was 10(9) M-1, and the number of binding sites on HEY cells was 2 X 10(4) per cell. The monoclonal ...
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ABSTRACTIntracranial tumours often require radiotherapeutic approaches that differ from other sites. Their specific requirements merit a specialized discussion. A brief review of radiotherapy techniques to treat intracranial tumours is presented with emphasis on the author’s own experience and work, where appropriate. A clinical introduction is presented first followed by a description of bot...
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ژورنال
عنوان ژورنال: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
سال: 1976
ISSN: 0317-1671,2057-0155
DOI: 10.1017/s0317167100025737